TRIGLYCERIDE SERUM LEVEL IN NEONATES WITH LIPID PARENTERAL NUTRITION
Chairunnisa Harahap,Mahendra Tri Arif Sampurna,Kartika Darma Handayani,Dina Angelika,Martono Tri Utomo,Risa Etika,Agus Harianto
Department of Child Health Faculty of Medicine Universitas Airlangga Dr Soetomo Hospital Surabaya Indonesia
Background : Intravenous lipid emulsion is source of essential fatty acid and energy dense non-protein calories. It is important to optimize long-term growth and development in newborns. Hypertriglyceridemia is a complication associated with lipid parenteral nutrition in neonate. The aim of this study is to describe the effect of lipid parenteral nutrition based on triglyceride (TG) in Dr. Soetomo Hospital.
Material : Retrospective study from medical record all neonates receiving lipid parenteral nutrition admitted in NICU Soetomo Hospital in March-May 2018. Lipid parenteral started from 0.5 g/kg/day increased 0.5 g/kg/day until maximum 3 g/kg/day. Patient died before reaching full enteral feeding were excluded. Serum triglyceride measured weekly until reached full enteral feeding. Hypertriglyceridemia defined when serum triglyceride >200 mg/dL. Statistical analysis was carried out using chi square with 95% confidence interval (P <0.05).
Results : There were 50 neonates analyzed, preterm 37 (74%) and term 13 (26%). There were 3 (6%) patients suffered hypertriglyceridemia. Hypertriglyceridemia in first week occurred in 1 neonate whereas in second week occurred in 2 patients. All hypertriglyceridemia neonates were preterm. There were no significant differences hypertriglyceridemia related to gestational age and birth weight.
Conclusions : There are no significant differences hypertriglyceridemia related to gestational age and birth weight.