OBJECTIVE: Tuberculosis (TB) is the most frequent opportunistic infection among HIV/AIDS patients. This co-infection had became the world’s leading cause of death. We aim to identify the risk factors of TB co-infection among HIV/AIDS patients in Dr. Kariadi Hospital Semarang.
METHOD: We reviewed medical records of HIV/AIDS inpatient and outpatient from January to December 2018 in Dr. Kariadi Hospital Semarang. Beside clinical manifestation of TB, all patients underwent Tuberculine Skin Test (TST)  and Chest X-Ray. Data were analyzed by Fisher exact test. 
RESULT: Thirteen out of 55 (23,6%)  HIV / AIDS patients had TB coinfection.  Malnutrition was found in 84.6%, CD4 level <200 (cells/µL) was found in 46.2%, and 92.3% had positive TB contact.  All were significantly associated with TB co-infection in HIV patients with p<0.001, p=0.024, and p=0.001 respectively. While gender (p = 1.000), age (p = 0.310), and haemoglobine (p = 0.057) were not significant as the risk factors. All patients showed negative TST result. Chest X-Ray showed only 1 out of 13 (7,6%) patients had Pneumocystic Carinii Pneumonia (PCP), and the rest did not support Pulmonary TB.
CONCLUSION: Risk factors of TB co-infection among HIV/AIDS patients were malnutrition, low CD4 level, and TB contact history.