Objective: To explore the efficacy of a perinatal center established through obstetric-pediatric collaboration in the management of extremely preterm infants, and to provide clinical evidence for improving the survival rate and quality of life of these infants. Methods: Clinical data of 281 extremely preterm infants (gestational age < 32 weeks) born and treated in our perinatal center from January 2022 to December 2025 were retrospectively analyzed. Infants were divided into 7 groups according to gestational age, and survival rate and outcomes were compared among groups. Results: Of the 281 extremely preterm infants, 250 survived, with an overall survival rate of 88.97%. Survival rate increased significantly with increasing gestational age (P-trend < 0.001). The lowest survival rate (40.00%) was observed in the