Kartika Istiningtyas, Agustini Utari, Gatot Irawan Sarosa
BACKGROUND: Congenital anomalies (CAs) are a worldwide problem. They are major causes of infant deaths, chronic illness, and disability, especially in developing countries. Data on these anomalies are still poorly collected in developing countries. The study aimed to assess the frequency and identify the possible risk factors of congenital anomalies among newborn METHODS: A cross-sectional study was conducted in the Pediatric Department dr. Kariadi Hospital, Semarang during the period of January – December 2018, using chi-square test to analyze risk factors. The patient’s medical records were reviewed. A record review checklist was used to collect information on sociodemographic data and clinical information. CAs defined as structural or functional anomalies that occur during intrauterine life and can be identified prenatally, at birth, or later in life. RESULTS: CAs were found in 72 of 242 newborn (29,75%) hospitalized in perinatology department. MCAs and digestive system anomalies were the commonest with the prevalence of 30 (41.7%) and 21 (29.2%) infants, respectively. Hypertension in pregnancy showed as a significant risk factor for congenital anomaly prevalence (p:0.002, OR 0.17, CI 0.06-0.50). Mother’s age (p 1.000), mother’s gravidity (p 0.879), polihidramnion (p 0.662), antepartum bleeding (p 1.000), and infection on pregnancy (p 0.497) were not risk factors for congenital anomalies. CONCLUSION: MCAs and digestive system anomalies is the most common types of congenital anomalies. Risk factor didn’t find in this study. Even hypertension in pregnancy showed as a significant risk factor but OR 0,17, it means that hypertension was protective factor.