Inayah Djabir, Aizah Lawang, Dasril Daud
OBJECTIVE : Congenital Heart Disease (CHD) is the most common heart disease in children. This study aims to evaluate the role of BNP levels as a marker of heart failure in patients with acyanotic congenital heart disease left to right shunt using systolic ejection fraction. METHOD : This research is a cross sectional study, from Desember 2017-July 2018, at the Cardiology Division of the Department of Child Health Dr. Wahidin Sudirohusodo Hospital. Subjects divided into 2 groups, heart failure and without heart failure, then each was evaluated for age, sex, nutritional status,and BNP levels. Data were analyzed using SPSS 23, bivariately by Chi-square and Mann whitney analysis. RESULT: From a total of 60 subjects, heart failure was noted in 50% and without heart failure in 50%. The results of the bivariate analysis showed a significant difference in elevated BNP levels in patients with heart failure compared than those without heart failure with p=0,00 (p<0,01) (OR = 95,2 95%CI 10,928-830,856), sensitivity 96,7%, specificity 76,7%, possitive predictive value 80,6%, negative predictive value 95,8%. CONCLUSION: In our study, there is significant correlation between BNP levels and heart failure. The increased BNP levels can be valuable for early screening of patients with higher risk of heart failure.