OBJECTIVE: Congenital heart disease (CHD) is one of the most common congenital abnormalities leading t0 death. One of its complications is nephropathy. This study aimed to determine kidney function of children with congenital heart disease measured by glomerular filtration rate parameters (GFR) and proteinuria.
METHODS: Study subject were pediatric cardiology patients with CHD. Blood and urine samples were collected from each subject to be assessed for glomerular filtration rate (GFR) and proteinuria. Data were analyzed using descriptive statistical analysis and linear regression.
RESULTS:. 16 subjects, acyanotic CHD was more dominant than cyanotic one, 15 and 1 respectively. Most acyanotic CHD patients were diagnosed with ventricular septal defect (VSD) 31.3% and VSD combined with perimembran outlet (PMO) 12.5%. The mean glomerular filtration rate of patients is 129.14 ± 22.37. none of our study subjects had proteinuria. The linear regression analysis demonstrated no significant effect of CHD on kidney function (R2 = 0.006, p = 0.785)
CONCLUSION: In pediatric patient with CHD, their kidney function is not affected by CHD as measured by GFR rate and proteinuria.