OBJECTIVE: To describe management recommendation using a neonatal early onset sepsis calculator and the Center for Disease Control (CDC)/American Academy of Pediatrics (AAP) guidelines among culture proven positive on neonatal ? 34 weeks age of gestation (AOG) treated with EOS.
METHOD: A retrospective review study of the risk and management categories, from   331 infants ? 34weeks AOG who received antibiotics at birth who born at University of the East Ramon Magsaysay Memorial Medical Center Inc (UERMMMCI) newborn unit, were calculated using the EOS calculator and compared to current guidelines published by the CDC/AAP guidelines and compared to current practice within the institution.
DATA ANALYSIS: Chi square and kappa value agreement was used to determine the difference between treatment recommendations of NEOS calculator and CDC/AAP guideline
RESULTS: Of the 331 patients who received therapy, only 14.2% were recommended empiric antibiotics by the EOS calculator, compared to the 39% were recommended by the CDC guidelines (p=0.0000) (? = 0.372). Eleven patients were identified to have culture-positive sepsis.
CONCLUSION: The number of infants suspected with EOS and subsequently require antibiotic use at birth may be dramatically reduced with the use of the neonatal EOS calculator. This leads to a decreased need for laboratory tests and antibiotic stewardship. Further prospective trials are recommended.