Ref Number = PITIKA-ASPR0307
Anies Mediressia, Sri Kesuma Astuti, Azwar Aruf, Kgs Yangtjik, Fifi Sofiah
Tuberculosis (TB) is a contagious disease of respiratory tract, which often difficult to diagnose in children, with non specified clinical manifestations. Thorough clinical, bacteriological and radiological examination are needed to diagnoses TB in order to give prompt treatment even though they can be difficult to established especially in rural areas with limited resources. This study aim to report the clinical and radiological profile of pulmonary TB in children.
A descriptive study with retrospective design was conducted at pediatric ward in Dr. Mohammad Hoesin Hospital from July 2017 to September 2018. Data was taken from medical records of patients age less than 18 years old with presumed pulmonary TB. Clinical condition, radiological examinations, acid fast bacilli (AFB) staining of sputum and Xpert MTB/RIF results were examined.
Eighty seven children with presumed TB were enrolled. There are 20 confirmed TB cases based on AFB and/or Xpert MTB/RIF. The most clinical findings found in children with confirmed TB were decrease appetite (95%), decreased body weight (85%), malaise (80%), night sweat (60%), severe malnutrition (60%), prolonged fever (55%), lymphadenopathy (55%) and ronchi (50%). Radiological examinations show suggestive TB in 90% patients, most findings found were infiltrate (65%) and hilar lymphadenopathy (50%). 
This study showed that even though AFB and Xpert MTB/RIF results are important to decide TB treatment, they can only be found in less than 50% of presumed TB patient. Possible clinical manifestations, compatible radiological findings and expert opinion are needed to establish early and adequate treatment. Decrease appetite, decreased body weight, night sweat, prolonged fever, lymphadenopathy and severe malnutrition were found in more than half confirmed pulmonary TB patients, followed by cough and in almost 50% patients. Suggestive TB radiological findings were found in almost all confirmed TB patients.
Keywords: TB, AFB, Xpert MTB/RIF, diagnosis
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