Ref Number = PITIKA-ASPR0384
Fitrih Rahmawati, Maria Christine Florens, Sjamsul Arief, Bagus Setyoboedi
OBJECTIVE  Biliary atresia is characterized by total obstruction of extrahepatic biliary system. It can had a bad prognose untill end up with death if the diagnosis and intervention are delayed. The etiology and pathogenesis of biliary atresia is still unknown. Cholestasis is a pathological condition due to impaired secretion and excretion of bile duct into duodenum. The etiology should be found earlier in order to get better outcome.

METHOD  A descriptive study was treated in January 2018 – December 2018 in cholestatic infants aged 1-6 months whose came to Hepatology Outpatient clinic Dr. Soetomo Hospital. Liver biopsy and histopathological examination already done on cholestatic infants. Data was obtained from the medical record database system. Demographic data and patient characteristics were evaluated.

RESULT Thirty-four infants were obtained during the study period, include of 56.5% are girls. There were differences in body weight, age, birth weight, and gestational age. The
laboratory findings included serum levels of hemoglobin, conjugated bilirubin, alanine
transaminase, aspartate transaminase and liver biopsy. The radiologic examination included abdominal ultrasonography and cholangiography.

CONCLUSION Infants with cholestasis often ends in diagnosed with biliary atresia, after done required examination. Early diagnosis and immediate intervention needed to obtain a good outcome
Keywords: biliary atresia, obstruction, liver biopsy
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