Ref Number = PITIKA-ASPR0424
Yoseph Arif Putra, Vivekenanda Pateda
OBJECTIVE: Obesity in adolescents is associated with an increased risk of impaired glucose tolerance. Obesity are important risk factors of type 2 diabetes mellitus (DM). It has been demonstrated that obese adolescents with impaired glucose tolerance are at very high risk for developing type 2 DM over a short period of time. Therefore, a screening seems meaningful especially in high risk groups such as adolescents with obesity, relatives with type 2 diabetes mellitus, and clinical features of insulin resistance (acanthosis nigricans).There are several risk factors (number of large meals, snacks, activity, birth weight, parents' income, history of DM in parents) that can trigger impaired glucose tolerance and diabetes mellitus. This study was conducted to analyze the relationship between diabetes mellitus risk factors and Oral Glucose Tolerance Test (OGTT) in obese adolescent in Manado.
METHOD: This study is a cross-sectional analytic study undertaken at 3 junior high school in Manado. OGTT examination was conducted and questionnaire about DM risk factors was given to 83 obese adolescent (BMI ? 95th percentile)
RESULTS: From 83 obese adolescent, 10 adolescent experienced impaired glucose tolerance (12.04%),consists of 9 males (90%) and 1 female (10%). We found no acanthosis nigricans in all study subjects. There was a significant correlation between the number of large meals and OGTT (rs = 0.225, p = 0.021). There was a significant correlation between parents’ income and OGTT (rs = 0.195, p = 0.040). There was no significant correlation between snack, activity, birth weight, history of diabetes mellitus in parents with OGTT.
CONCLUSION: In this study, 12.04% of obese adolescents experienced impaired glucose tolerance. The number of large meals and parents' income are risk factors for impaired glucose tolerance in obese adolescents in Manado.
Keywords: Obesity, OGTT, risk factor, manado, children
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