Ref Number = PITIKA-ASPR0426
Ayu Asyifa RF, Krisna Tsaniadi, Asri Purwanti, Agustini Utari
OBJECTIVE: Craniopharyngioma is a common benign tumor in sellar area and mainly originates from pituitary and pituitary stalk, accounting for up to 3% of all intracranial tumors. Most patients with hypothalamus pituitary disorder are likely to have endocrine dysfunction. The aim of our study to discuss our experience with patients who underwent tumor resection from January 2018 to March 2019 based on a series of 7 patients.
METHOD: We retrospectively analyzed the clinical and laboratory characteristics at the time during treatment and evaluated 7 craniopharyngioma patients in Dr. Kariadi Hospital Semarang Central Java between 2018 and 2019 using medical record. 
RESULT: The patients (6 male, 1 female) were aged between 2  - 14 years old who underwent surgery with pathological result craniopharyngioma. Two patients (28,5%) diagnosed with hypothyroid but five patients (71,4%) has no data laboratory of thyroid hormone. Electrolyte imbalance was found in all patients, preoperative data found three patients (42,8%) with hypernatremia. Two patients (28,5%) diagnosed with diabetes insipidus. Three patients (42,8%) had short stature, while the remaining (57,1%) had a normal height.       
CONCLUSION: As a common pathology which is involving the hypothalamic-pituitary axis, endocrine dysfunction is often found in craniopharyngioma patients. Multidisciplinary approach and long-term careful monitoring are needed to manage pre, peri, as well as post-operative endocrine problem.
Keywords: craniopharyngioma, endocrine
Disclaimer: The Views and opinions expressed in the articles are of the authors and not of the journal.
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