Meilianawati, Rina Agustina, Inge Permadhi, Safira Alatas
OBJECTIVES: to investigate the level of non-high-density lipoprotein cholesterol (non-HDL-c) concentration and its related factors among adolescents of urban Jakarta. METHODS: This study was part of a 10 years follow-up of Probiocal (probiotic and calcium) study that was conducted between January to March 2019. We examined 152 adolescents, aged between 11-17 years old who resided in 20 communities in East Jakarta. Adolescents were interviewed by researcher for socio-demography and physical activity questionnaire. Total energy, fat, and fiber intake were collected by 3-days 24 hours recalls and semi-quantitative food frequency questionnaire. Anthropometrics (weight, height, and waist circumference) were assessed. Total serum cholesterol and high-density lipoprotein (HDL) cholesterol concentration were determined after overnight fasting to calculate non-HDL-c concentration. Age, gender, biological maturity, family history of cardiovascular diseases, maternal education status, and family income were also assessed as potential related factors. Linear regression analysis was performed to investigate the related factors of non-HDL-c concentration. RESULTS: The average of non-HDL-c concentration was 103 mg/dL. Family history of cardiovascular diseases (p = 0.046), maternal education status (p = 0.045), obesity (p = 0.033), waist circumference (p = 0.020), and fat intake (p = 0.040) were positively associated with non-HDL-c concentration. There were no significant gender-related differences in non-HDL-c concentration. CONCLUSION: The concentration of non-HDL-c in adolescents are determined by family history of cardiovascular diseases, higher maternal education status, obesity, waist circumference, and fat intake. That factors should be considered in the future evaluation of non-HDL-c level. Modifying that factors may contributed to the good variance in non-HDL-c concentration and reduce cardiovascular risk in adolescents.