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Abstract Ref Number = APCP1035
Poster Presentation
NEONATAL SWEET’S SYNDROME
Fadhilah Syekh Abubakar, Ema Alasiry, A Dwi Bahagia Febriani, Adhariana HK
Departement of Child Health, Faculty of Medicine Hasanuddin University Dr Wahidin Sudirohusodo Hospital, Makassar, Indonesia
Background : Sweet syndrome is an inflammatory disease characterized by fever and inflammatory skin lesions (painful erythematous plaques with a dermal neutrophilic infiltrate), and blood neutrophilia. This condition is rarely in children. It presents in three clinical settings: classical Sweet’s syndrome, usually after a respiratory tract infection; malignancy-associated, frequently related to acute myelogeneous leukemia; and drug-induced. We present, to the best of our knowledge, the first case sweet’s syndrome in neonatal at Makassar.
Case Presentation: A 29-day-old baby boy was hospitalized with erythematous nodules and plaque, bloody diarrhea, fever, cough and dyspnea. Extracutaneus manifestation was paralysis of facial nerve, bilateral perforated otitis media, acute kidney injury, and hepatomegaly. Diagnosis was based on the presence of major criteria: rapid onset of characteristic skin lesions which are tender erythematous plaques and nodules. The minor criteria are fever, history of upper respiration infection, and very good response to corticosteroid. Abnormal laboratory findings were white blood cell count >8×103/L, neutrophils >70%, and high C-reactive protein. This syndrome responded promptly upon corticosteroids.
Learning Points: Neonatal Sweet’s syndrome is a rare disease. Symptoms and signs at the age of the first 4 weeks of life may be associated with systemic disease and genetic associations. Sweet's syndrome in the neonatal period often heralds a serious underlying disorder and requires thorough investigation.
Keywords: Sweet’s syndrome Neonatus Skin inflammatory lesion Neutrophilic dermatosis
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