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Volume 5, Jan - Mar 2022
Malnutrition - a threat to our children in 2022 and beyond??
Shakila Zaman
Adequate nutrition is essential for children’s health and development. Globally it is estimated that undernutrition is responsible, directly or indirectly, for at least 35% of deaths in children less than five years of age. Undernutrition is also a major cause of disability preventing children who...
INTERVENTION OF PHYSICAL ACTIVITIES IN CHILDREN AND ADOLESCENTS WITH OBESITY IN ASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
Connie Raina Carissa 1, Annang Giri Moelyo 1, Dwi Hidayah 1
Background The prevalence of obesity in children and adolescents in developing countries, especially in Asia, is increasing and becomes a significant cause of morbidity and mortality, including in Indonesia.1 Objective: This study aims to analyze the intervention of physical activities on BMI, wais...
Anthropometric assessment parameters in children with disease-related malnutrition
Yoga Devaera 1, Rahmat B. Kuswiyanto 2, Murti Andriastuti 1
Nutritional status assessment and monitoring in pediatric disease related malnutrition, especially congenital heart disease (CHD) and cancer, have certain challenges. Until now, there is no consensus regarding standard nutritional assessment parameters and monitoring for pediatric DRM. Weight measur...
Pathogens in acute respiratory failure in the pediatric intensive care unit in Tokyo, Japan, 2015-2017
Keiko Soneda, 1 Yuta Aizawa, 1,2 Kazuhiro Uda, 1,3 Kenta Ito, 1,4 Takayuki Sueishi, 5 Yoshihiko Morikawa, 6 Kazue Kinoshita, 7 Naoki Shimizu, 5,8 Yuho Horikoshi 1
This is a prospective study that investigated the etiology of acute respiratory failure using real-time PCR in a PICU in Japan. It is the largest of its kind ever to be conducted in a Japanese PICU. We found that viruses were the main cause of acute respiratory infection, accounted for 46%. RS virus...
Phelan McDermid Syndrome : A Case Report
SH Dalwai 1, A Rohil 1, B Chawla 1, MR Garg 1, R Merchant 2
Background: Phelan McDermid syndrome (chromosome 22q13.3 deletion) is a neurodevelopmental disorder presenting with global developmental delay (GDD)/Intellectual Disability (ID) and autism spectrum disorder (ASD) with multi-systemic involvement of varying severity. Aims: By highlighting this case ...
Van Wyk Grumbach Syndrome in a 7-year-old girl: a case report
Lina Purnamasari 1, Indra Widjaja Himawan 2, Iwan Darma Putra 3
Van Wyk Grumbach syndrome (VWGS) is rare syndrome, characterized by hypothyroidism, delayed bone age, isosexual precocious puberty and ovarian cysts. The symptoms completely reverse back to pre-pubertal state after treatment with thyroxin. This case report illustrates a seven-year-old girl who was r...
Spinal Intramedullary Tuberculosis (SIMT) in 13 Years Old Girl
Ameliana 1,2, Rinna W. Sundariningrum 2, Darmawan Budi Setyanto 2,3
Abstract Background. Tuberculosis (TB) is one of top 10 causes of death due to communicable diseases worldwide. Indonesia is one of 30 countries with the highest cases of TB worldwide. In 2019, there were 63.111 (11%) cases of TB in children 0-14 years old. Central Nerve System (CNS) involve...
Acute abdomen in children: Never miss the diagnosis 7 ovarian torsion in a girl child
Kiran B 1, Praveen T 1, Suman M G 1, Santosh S 1, Kaleem Ullah S 1, Kalavathi D Biradar 1, Rathi Priya 1
Ovarian torsion represents an important differential diagnosis for acute abdomen in children. Prompt diagnosis and early surgical management is required to prevent further adnexal damage. The clinical presentation mimics other pathologies, such as appendicitis. We report a case of 10year girl pre...
Volume 4, Oct - Dec 2021
Psycho-social Impact of COVID-19 on Children
Naeem Zafar
This is an editorial on the Psycho-social Impact of COVID-19 on Children as there are two articles submitted on the same subject in this issue and as this topic is important in the current scenario...
The Relationship between Soil-Transmitted Helminth Infection and the Behavior of Elementary School-Aged Children
Primadiati Nickyta Sari 1, Bambang Soebagyo 1, Husnia Auliyatul Umma 1
Abstract Background Soil-transmitted helminth (STH) infection among elementary school-aged children can cause long-term effects on brain development, including future behavioral disorders. Currently, there are no studies that reveal the effect of STH infection on behavioral development disorders in...
Early predictors of diphtheric cardiomyopathy in children leading to better survival: Is there any solution?
Usman Rashid 1, Rashid Nawaz 2, Fazal Ilahi Bajwa 2, Tahir Mahmood 2, Zile Fatima 1
“Early predictors of diphtheric cardiomyopathy in children leading to better survival: Is there any solution?". Background and objective Diphtheria remains a fatal disease in the current era of wide spread immunization and an important cause of pediatric mortality in developing countries. Acute ...
Cryptorchidism in Infant & Children at Dr. Hasan Sadikin General Hospital Bandung
Novina Novina 1, Nurrahman Agung Prakoso 2, Adi Imam Cahyadi 3, Nadia Pramudani 4
Cryptorchidism is a congenital disorder that occurs when one or both testicles do not descend completely toward the bottom of the scrotum. The purpose of this study was to describe the clinical manifestation of cryptorchidism cases in infants and children at dr. Hasan Sadikin General Hospital (RSHS)...
Efficacy of Psychological First Aid Training on the Perceived Competence of Frontline Workers during COVID-19 Pandemic
Naeem Zafar 1,2,3, Mehek Naeem 1,2,3, Andleeb Zehra 1,2, Uzma Ashiq 1, Neelam Zohaib 1, Mohammad Moaz 1,3, Muhammad Imran 1
This study is an attempt to explore, document, and share the learnings from our work with front-line workers who were on the frontline during the COVID19 pandemic. It attempts to describe their perceived competence after a Psychological First Aid Training...
Child Protection in Context of COVID-19 Pandemic: Practice Guidelines for Pediatricians
Rajeev Seth 1, Preeti Galagali 1, Jordan Greenbaum 2, Riti Chandrashekhar 1, Sandhya Khadse 1, Uma Nayak 1, Shekhar Seshadri 3
Child Protection in Context of COVID-19 Pandemic: Practice Guidelines for Pediatricians Background: Pediatricians are likely to encounter children who have suffered instances of abuse and neglect on account of societal changes due to the COVID-19pandemic. There is an urgent need to up skill pedia...
Successful mesna intra catheter treatment in hemorrhagic cystitis post chemotherapy patients
Sjakti HA 1, Utama IIN 1
Cyclophosphamide and ifosfamide are commonly used alkylating antineoplastic agents for chemotherapy with common side effect of causing hemorrhagic cystitis in children. Incidence rates between 7% and 70% have been reported in children with hemorrhagic cystitis. Case report 1 A 7 years old boy wit...
Challenges For The Breastfeeding Mother Amidst The Covid-19 Pandemic – Vaccination Vs Infant’s Allergy
Aw-Zien Toh 1, Benjamin Wei-Liang Ng 2, R Mark Beattie 3, Teck-Hock Toh 1
COVID–19 has made things more complicated, but still, common things occur commonly. Many conditions share symptoms and signs, but when a common diagnosis seems likely, it usually the right one. Indeed, Occam’s razor advocates that when there are multiple hypotheses for one prediction, we should ...
Volume 4, Jul - Sep 2021
The Psychological Impacts on Adolescents During COVID Pandemic Requiring Proper Attention and Immediate Action
Lilian WONG
COVID-19 was a novel coronavirus firstly evolved in late 2019 and rapidly spread all over the world affecting everyone in this planet. While science has highlighted the physical damages, the infectivity, and the socioeconomic burdens, the negative psychological impacts arisen directly or indirectly ...
Peutz-Jeghers Syndrome: Current State-of-the-Art
Cipta Mahendra
Peutz-Jeghers Syndrome (PJS) is rare hereditary disease. Mucocutaneous pigmentations and gastrointestinal polyps are the most prominent features. To date, the only approved treatment for this syndrome is to eliminate the polyps found during the extensive inspection of the patient’s body by snare e...
Profile of Popular Tweets During the 2019 Philippine Poliomyelitis Outbreak
Cyrus Cesar R. Tejam
The consumption of potentially harmful information shared in social media during outbreaks can leave children at an increased risk of acquiring vaccine-preventable diseases. Exploring the characteristics of the most popular tweets during the outbreak of poliomyelitis in the Philippines in 2019 can g...
Knowledge and Awareness of Autism Spectrum Disorder among Paediatricians and Primary Healthcare Professionals in Singapore
Sharline SUHUMARAN 1, Geraldyn LEONG Kit Ying 2, Chui Mae WONG 1
Autism Spectrum Disorder (ASD) is the leading cause of disease burden in children between ages 0 and 14 years in Singapore. Early identification and intervention confers a better prognosis. This study aims to evaluate ASD awareness among paediatricians and primary healthcare professionals in Singapo...
To observe the residual leak after Transcatheter closure of PDA with different types of duct occluders.
Khizra Mehmmood 1, Syed Najam Hyder 1, Manawer Ghous 1
Patent ductus arteriosus has very diverse morphology and sometimes it becomes challenging at times to occlude along with certain complications Transcatheter closure of PDA is the procedure of choice and is consider safe. Various devices develop to occlude PDA because of diverse morphology. These dev...
Cerebral Venous Sinus Thrombosis: Clinical Profile, Risk Factors, Neuroimaging Results, and Treatment Outcomes in the Pediatric Population
Huda Sardar 1, Haidar Sultan 2, Tipu Sultan 2
Cerebral venous sinus thrombosis (CVST) consists of acute thrombosis (blood clot formation) in the dural venous sinuses, that drain blood from the brain. Cerebral venous drainage involves the movement of blood through the superficial and deep systems into the jugular veins. An enlarged thrombus res...
Ramsay Hunt Syndrome: A Case Report
Syahmi Amar 1, Rustam Siregar 1, Husnia Auliyatul U 1
One of the types of cranial Herpes Zoster is herpes zoster oticus. It is rarely found in children with possible clinical manifestations include vesicular lesions according to dermatome and peripheral facial nerve paralysis. The combination of all these symptoms is known as the Ramsay Hunt Syndrome ...
Ankyloblepharon filiforme adnatum in a neonate
Kaushik Shatilal 1, Pooja Hymn Parikh 2
We report the case of a rare congenital anomaly of the eyelid called Ankyloblepharon filiforme adnatum (AFA). A thorough clinical examination is needed to rule out other associated anomalies. An early diagnosis and management can lead to prevention of a stimulus deprivation amblyopia which can have ...
Volume 4, Apr - June 2021
Quality Improvement ... Provision of Uniform Quality Care
Dr Bakul Jayant Parekh
Quality Improvement … Provision of Uniform Quality Care Dr Bakul Jayant Parekh Safety of patients and quality of healthcare are of utmost importance for us the healthcare providers. In our earlier article published in Indian Pediatrics, Rhishikesh Thakre and I define healthcare quality as “ h...
Participation in Childhood Occupations for 6 to10 years old children – The translation and psychometric evaluations of the PICO Malay version
Siew Yim Loh 1, Su Im Ee 2, Mary J. Marret 3, Mahmood Danaee 4
Dear editorial staff We have corrected the manuscript per the reviewer's suggestion and corrected the title of tables/figures with footnotes Thank you ...
Disease Burden of Virus-associated Lower Respiratory Tract Infections among Hospitalized Children Under Five Years of Age in Sarawak
Jakie Ting 1, 2, Sing-Ling Kong 3, Tiing-Tiing Chua 2, Tiana Ti 3, Jane K. Fieldhouse 4, 5, King-Ching Hii 3, Gregory C. Gray 4 , 5, 6, 7, Teck-Hock Toh 1, 2, 8
Disease burden of a total of 196 children with virus-associated lower respiratory tract infections (LRTIs) in Central Sarawak was studied. We found that among under-five children with LRTIs, respiratory syncytial virus was the most prevalent viral etiological cause, but adenovirus infection was asso...
Clinical profile and outcome of acute pancreatitis in Filipino children
Emaluz Z. Parian 1, Marilou G. Tan 1, Maria Estela R. Nolasco 1, Randy P. Urtula 1
Pediatric acute pancreatitis has been reported to show an increasing incidence worldwide. Determining local data on clinical profile, factors, severity and outcome would help improve recognition, diagnosis and management of this emerging disease....
Quality of Life in Congenital Adrenal Hyperplasia with Disorders of Sex Development: Case Series
Nur Rochmah 1, Muhammad Faizi 1, Dedy Setiawan 1
Quality of Life in Congenital Adrenal Hyperplasia with Disorders of Sex Development: Case Series...
Comparison of effect of Prophylaxis Therapy and On Demand Therapy on Joint Bleeding Episodes in Children With Hemophilia in Moewardi Hospital, Surakarta
Dhimas Naufal 1, Muhammad Riza 1, Yulidar Hafidh 1
Factor replacement therapy is the primary treatment in children with hemophilia. Factor replacement is classified into two categories, prophylactic treatment and on-demand treatment. The administration of these two therapies may vary in any hemophilia center based on the availability and stakeholder...
An Association Between Physical Activity and Sleepiness
Jun Kohyama
Dear editor-in-Chief, Asia Pacific Journal od Pediatrics and Child Health. Here I, Jun Kohyama, a sole author of this manuscript, submit a paper entitled “An association between physical activity and sleepiness” as a brief report for Asia Pacific Journal of Pediatrics and Child Health. This m...
The effects of public health measures for COVID- 19 on a child with Attention Deficit Hyperactivity Disorder in Northern Sri Lanka
Surenthirakumaran R. 1, Sasrubi S. 1
Submission of case report I would like to submit the case report entitled, “The effects and management of quarantine due to COVID- 19 on a child with Attention Deficit Hyperactivity Disorder in Northern Province, Sri Lanka”. The authors are Rajendra Surenthirakumaran, and Sasrubi Sathees to be ...
Volume 4, Jan - Mar 2021
Solving Stunting in Children as A Medical, Social, Economic, Political, and Emotional Problem
Aman B Pulungan 1
Growth of Indonesian children has been documented since the start of the 20th century. Stunting is defined as body height/length below 2 standard deviations for age in the WHO standard growth chart, caused by malnutrition or other health problems. Indonesian children are found to be shorter than int...
Normal Plasma Zinc Level In Correlation With Length Velocity In Stunting Children Aged Between 1 And 2 Years Old In Surakarta
Aldilla Dinaresti 1, Harsono Salimo 1, Fadhilah Tia Nur 1
ABSTRACT Background. Stunting is a chronic malnutrition problem caused by prolonged duration of insufficient nutritional intake due to feeding inappropriate to nutritional needs. Malnutrition in children increases the mortality in infants and children, causing susceptibility to illness and non-opti...
Establishing Normal Echocardiographic Measurements In Healthy Indian Newborn Infants
Atanu Roy Chowdhuri 1, Soumyojit Saha 1, Sudipta Mondal 1, Dipanjan Bhattacharya 1
Introduction: Establishing normal values is fundamental for further analysis and assessment. The echocardiograph is an essential tool for cardiac evaluation and progress in pediatric cardiology has made this investigation more inevitable than before. However, normal values in neonatal cardiology are...
Breastfeeding self-efficacy: relationship with planned behaviors in mothers of NICU newborn Breastfeeding self-efficacy in NICU.
Ali Mohsenzadeh 1, Monirsadat Nematollahi 1, Roghayeh Mehdipour Rabory 1, Mansooreh Azzizadeh forouzi 1
Dear editor I am pleased to submit our manuscript, original research, entitled Breastfeeding self-efficacy: relationship with planned behaviors in mothers of NICU newborn Breastfeeding self-efficacy in NICU. ...
A Rare Case of Common Variable Immunodeficiency in Children Mimicking Sarcoidosis
Dr. Sunil V. Kapur 1, Dr. Jitendra S. Oswal 1
Common variable immunodeficiency (CVID) is the most prevalent clinically significant antibody deficiency in children. It is characterized by a low serum immunoglobulin IgG and a low IgA and/or low IgM resulting in recurrent and severe infections, associated in some cases with autoimmune manifestatio...
A rare case of interstitial lung disease as a presenting feature in Juvenile Systemic Lupus Erythematosus responding to Mycophenolate Mofetil
Sunil V 1, Jitendra S. Oswal 1
ABSTRACT: Background: Symptomatic interstitial lung disease (ILD) is rare in systemic lupus erythematosus (SLE) and there is no established treatment for it. Data is limited to adult lupus patients. Aim: The aim of this case report is to highlight that ILD can be as a presenting feature in juve...
Pediatric Chronic Fibular Pandiaphyseal Osteomyelitis: Case Report With Literature Review
Angelo Carlo M. Ostrea 1, Miguel David R. Ramos 1, Rodolfo V. Frez 1
Osteomyelitis is an inflammatory condition affecting the bone and bone marrow, brought about by an infection. Delay in presentation in children usually results in chronic osteomyelitis, requiring surgery and chemotherapy. Staphylococcus aureus is the most commonly isolated organism in these cases, w...
Volume 3, Oct - Dec 2020
Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19
Antonius H. Pudjiadi1
Pandemic of coronavirus disease 2019 (COVID-19) associated with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is rapidly evolving. As of December 2020, 10.3 % of all reported COVID-19 cases in US represents paediatric cases. There were concerns regarding reports on hyperinflammatory s...
Correlation Between Systemic Lupus Erythematosus Disease Activity Index Score and Anti-Mullerian Hormone Level in Pediatric Systemic Lupus Erythematosus Patients
Hamid Pramusyahid 1, Diah Lintang Kawuryan 1, Sri Lilijanti Widjaja 1, Annang Giri Moelyo 1
Background: There is a scoring system to assess the activity of systemic lupus erythematosus (SLE) disease, known as systemic lupus erythematosus disease activity index (SLEDAI). SLE patients are at risk of amenorrhea, which may lead to infertility. The anti-Müllerian hormone is used as a marker fo...
Effects of Vitamin D Supplementation and Systemic Lupus Erythematosus Disease Activity
Syahmi Amar 1, Annang Giri Moelyo 1, Diah Lintang Kawuryan 1
Background: Systemic Lupus Erythematosus (SLE) patients tend to experience vitamin D deficiency in attribution to several factors. However, studies linking vitamin D levels and SLE disease activity in children are still lacking, particularly in Indonesia. Objective: This study aims to analyze the...
Shift to online teaching during covid-19 – early challenges and immediate measures undertaken by teachers in india
Manish Rammohan Garg 1, Deepti Kanade-Modak 2, Sandhya Kulkarni 3, Kamini Prakash Rege 4, Samir Hasan Dalwai 4
Introduction Schools across India in March 2020 had to suddenly switch to online teaching due to unprecedented COVID-19 pandemic lock down. This sudden transition led to multiple challenges for teachers. Objectives To determine the understanding of primary and secondary grade teachers in urban...
Epidemiological Characteristics, Clinical Spectrum And Outcomes Of Covid-19 In Cohort Of 50 Patients Of Pediatric Age Group Hospitalized In A Tertiary Care Hospital: A Retrospective Study
Prof. Dr. Rai Muhammad Asghar 1, Dr. Muddasar sharif 1, Dr. Khalid Saheel 1, Dr. Rai Rijjal Ashraf 1, Dr. Muhammad Hussain 1, Dr. Abid Hussain 1
Abstract Introduction Covid 19 after it was first reported in china spread across most part of the world in short span of time. As the cases began to increase, newer data continue to emerge giving new insights to this disease. The pediatric population is at particular risk to any epidemic. Data ...
Premature infant with hydranencephaly: a first reported case in Indonesia
Azizah Hamida 1, Andi Arwan A 1
This case presented a 1,300 g male infant who was born by induced labor at 30 weeks gestation due to fetal distress. Prenatal and postnatal ultrasound of the newborn led to the diagnosis of hydranencephaly, which includes: replacement of cerebral hemispheres with fluid accumulation, the presence of ...
COVID-19 associated with Multi-System Inflammatory Syndrome in Children (MIS-C) combating panic with facts: A case report
Abdul Jabbar 1, Manzoor Hussain 2, Mohammad Abdullah Al Mamun 3
In December 2019, an outbreak of pneumonia of unknown origin developed in Wuhan of Hubei Province, China.1-3 By January 7, 2020, Chinese scientists confirmed that the outbreak was caused by a novel coronavirus, severe acute respiratory syndrome-related coronavirus 2 (SARS- CoV-2), and the disease...
COVID’19: A threat to the nervous system in children
Monir Hossain 1, Manifa Afrin 1, Mahfuza Shirin 1, Abdur Razzaque 1, Shiplu Kumar Das 1, Sultana Razia 1, Nayeema Roshni 1
COVID’19 (SARS-CoV-2) is a pandemic disease all over the world. Peripheral neurological complications of COVID-19 in children have not been reported yet. A presenting symptom or complication of COVID-19 as GBS has not been described in pediatrics age group. We report a case of a 3-year-old boy ...
Volume 3, Jul - Sep 2020
Vaccine Trust – What critical role can healthcare professionals play?
Naveen Thacker1, Shraddha Uttekar 2
The editorial states that it is essential to recognize that confidence and trust plays a central role in vaccine acceptance. The significant contribution of the wave of infodemic during the COVID-19 pandemic, in the fall of confidence in vaccines, brings the urgent need to assess, examine, and analy...
Transcatheter Closure Of Atrial Septal Defects In Myanmar Children, Initial 3 Years’ Experience
Hnin Le Phyu 1, Khin Maung Oo 1, Ohnmar Ko 1, L Jaryung 1, Nu Htar Wai 1
This manuscript is a report of original clinical interventions focused on pediatric community and can be referred as cost effectiveness analysis in the treatment of congenital heart disease. ...
Diagnostic Value of Rodwell Hematological Scoring System Compared to Neutrophil Lymphocyte Count Ratio (NLCR) in Diagnosing Early Onset Neonatal Sepsis
Pitra Sekarhandini 1, Dwi Hidayah 1, Annang Giri Moelyo 1
ABSTRACT Background: Neonatal sepsis is still a burden health problem worldwide due to its high morbidity and mortality. Clinical symptomps are unspecified. Blood culture is still a gold standard in diagnosing neonatal sepsis, though its process requiring time. Initial diagnostic of early onset neo...
Correlation between Serum Zinc Levels and Severity of Atopic Dermatitis
Debby Andina Landiasari1, Diah Lintang Kawuryan1, Dwi Hidayah1
Abstract Background Atopic dermatitis is an inflammatory skin disease commonly found in children with unknown etiology. Zinc is an important element that plays a major role in the immune system. The effect of zinc deficiency can be detrimental because it affects the growth and function of immune ce...
Platelet count as predictive factor of renal involvement in Pediatric Henoch-Schonlein Purpura
Jessica Kireina 1, Reni Ghrahani 2, Sri Suryanti 3
The aim of this study is to analyze the usefulness of increasing platelet count as a predictive factor of renal involvement in pediatric Henoch-Schonlein Purpura. Renal involvement is one of the most severe manifestation in HSP. Inflammation is a major indicator of severity in Henoch-Schonlein Purpu...
Review of COVID 19 data and mitigation efforts in India
Digant D Shastri 1, Dipsa D. Shastri1
From its first reported case on 30th January, 2020, India took 58 days to record 1,000 cases. It crossed 10,000 in another 16 days. From there to 1,00,000 was breached in 35 days. Since then the number of days to add an additional lakh cases has progressively gone down. India had a total of 571 cas...
Caffey Disease mimicking as an osteomyelitis of ulna: A Case Report
Darshak Makadia 1, Sanjay Naik 1
Caffey’s disease or Infantile Cortical Hyperostosis (ICH) is a rare and mostly self limiting condition affecting young infants. 5 months old baby boy presented to our hospital with complains of fever, swelling in left forearm, irritability for 3 days. Initially he was treated as an osteomyelitis a...
Chronic Granulomatous Disease presenting first time in newborn period as neonatal sepsis due to staphylococcus aureus infection: A rare presentation.
Sudhir Mehta 1, Praveen Kumar 1
Chronic Granulomatous Disease is characterized by defective intracellular bacterial and fungal killing in neutrophils and monocytes. It is caused by defects in NADPH oxidase, the enzyme complex responsible for generating the phagocyte respiratory burst. Catalase positive organisms can cause severe ...
Volume 3, Apr - Jun 2020
The COVID-19 Pandemic and Asia-Pacific Children
Aman B Pulungan1
Dear Editor in Chief, We hereby submit our editorial note on COVID-19 and Asia Pacific Children. Thank you. Aman B Pulungan amanpulungan@mac.com...
COVID-19 in children in Bangladesh: Situation analysis
Manzoor Hussain1, Mohammad Abdullah Al Mamun2
Comparing to adults, so far the direct effects of COVID-19 on child and adolescent appears not significant. COVID-19 outbreak adversely affect different services among the children of Bangladesh. These include disruption to their healthcare, nutrition, protection, education, overall mental wellbeing...
How common is Hypothyroidism in Children with Epilepsy on Antiepileptic Drugs
Nur Rochmah1, Muhammad Faizi1, Nur Nailul1, Prastiya Indra Gunawan1
Abstract Background:Epileptic children treated with oral antiepileptic drugs (AEDs) are at risk of hypothyroidism. However, there are still limited data about the influence of AEDs on thyroid function in children. Aims:To analyze thyroid function of epileptic children. Methods:A cross-sectional s...
OOSTENBRINK SCORE FOR DETECTING BACTERIAL MENINGITIS IN CHILDREN AT DR. MOEWARDI HOSPITAL
Arifatun Nisa1, Fadhilah Tia Nur1, Ganung Harsono1
Background: The clinical symptoms of bacterial meningitis are very broad, non-specific and there are no obvious symptoms. The diagnosis of the aetiology of meningitis in areas with limited resources is still constrained by several things. Several clinical predictors can help predict the incidence of...
ULTRASONOGRAPHIC FINDINGS IN CHILDREN WITH DENGUE FEVER ADMITTED TO A TERTIARY CARE HOSPITAL IN RAWALPINDI DURING 2019 OUTBREAK
Rai Muhammad Asghar1, Rai Rijjal Ashraf1, Mudassar Sharif1, Muhammad Hussain1, Abid Hussain1
Dengue fever is one of the most important emerging vector-borne viral diseases. There are four serotypes of dengue viruses, each of which is capable of causing self-limited dengue fever or even life-threatening dengue hemorrhagic fever and dengue shock syndrome. The aim of this study was to evaluate...
Prevalence and disease severity of multiple respiratory pathogens among children with severe lower respiratory tract infection
Lee Jeffrey Soon-Yit1,2, Chua Tiing-Tiing1, Ting Jakie1,2, Wong See-Chang2,3, Chieng Chae-Hee2,3, Toh Teck-Hock1,2,3
A review of case records of children with severe lower respiratory tract infection (LRTI). We described the prevalence of children with severe LRTI who had multiple concurrent respiratory pathogens. The impact of multiple respiratory pathogens on the ventilator requirements, duration of ventilation ...
Dynamic of maternal vitamin 25(OH)D and 1,25(OH)2D level throughout pregnancy in small for gestational age infant: a cohort study of vitamin D impact on pregnancy in West Java- Indonesia
Setyorini Irianti1, Raden Tina Dewi Judistiani2, Sylvia Rachmayati3, Jusuf Sulaeman Effendi1, Budi Setiabudiawan4
ABSTRACT Different reports of Vitamin 25(OH)D and vitamin 1,25(OH)2D level in pregnancy showed different impact to pregnancy outcome. Those different results suggested a possible dynamic of vitamin D level throughout pregnancy which play role in pregnancy outcome. In this study, we describe differ...
GLUTARIC ACIDEMIA TYPE II IN A FILIPINO SCHOOL AGE CHILD
Leniza G. De Castro-Hamoy 1,2,3, Juan Carlo C. Viado 1, Novette Regina M. Lagunzad 1,3
Glutaric Acidemia type II is a rare hereditary metabolic disorder involving fatty acid oxidation and amino acid metabolism. Symptoms can range from severe neonatal life-threatening events which may include physical abnormalities and acidosis to milder, late-onset presentations. The aims of this repo...
Volume 3, Jan - Mar 2020
Coronaviruses and The Current Pandemic
Muhammad Ashraf Sultan1, Muhammad Faheem Afzal2
Coronaviruses are enveloped non-segmented positive-sense RNA viruses belonging to the family Coronaviridae and the order Nidovirales....
Clinical accuracy of Non-contact infrared thermometry in febrile Indian infants
RajeshwarBalaji1, Srinivasan Thiagarajan1, Vijaya Chavada2, Sriram Pothapregada1
OBJECTIVE: To compare the clinical accuracy of Non-contact infrared thermometer with digital thermometer. METHODS: This analytical cross-sectional study included two hundred and fifty febrile infants(less than 1 year of age) in a tertiary health care facility for a period of two months. Random Sam...
Post Term Gestational Age and Non Exclusive Breastfeeding are Risk Factors for Atopic Dermatitis in The First 3 Months of Life. A Study From Bali Province-Indonesia
Bagus Ngurah Mahakrishna1, Ketut Dewi Kumara Wati1, Zakiudin Munasir1, Budi Setiabudiawan1, Kadek Ayu Lestari1, Hendra Santoso1, Komang Ayu Witarini1
Abstract: Background: Studies reported that Atopic Dermatitis (AD) start to occur during the first 3 months of life. Our preliminary study shown that post term birth giving high risk for the development of AD. Hence we did the study to cover post term birth together with other known factors for the...
Does Functional Constipation Affect Growth Status in Children? - A "cross sectional" pilot study
Md. Benzamin1, Masud Rana2, A.T.M Mijanur Rahamn2, Kaniz Fathema1, Rubaiyat Alam1, Asaduzzaman Asad2, Maria Kibtiar3
To The Editor Asia Pacific Journal of Pedaitrics and Child Health Subject: Submission of manuscript. Dear Sir, I am submitting a manuscript entitled, “Does Functional Constipation Affect Growth Status in Children? - A Cross sectional pilot study” for publication in your journal. This res...
Correlation Between Goiter Size and Quality of Life in Children and Adolescents with Hyperthyroidism in Dr. Hasan Sadikin General Hospital Bandung
Nadhira Nizza Hanifa1, Guswan Wiwaha2, Novina3
This study was carried out to determine whether there is a correlation between the size of goiter and the quality of life of patients with hyperthyroidism, especially in children and adolescents patients with hyperthyroidism at Hasan Sadikin General Hospital (RSHS), Bandung, West Java, Indonesia....
Diagnostic value of Tumor Necrosis Factor - Alpha in cerebrospinal fluid differentiates bacterial from viral meningitis in children
Masayu Lubna Anniazi1, Fadhillah Tia Nur1, Sri Lilijanti Widjaja1
Background: The incidence of pediatric meningitis in Indonesia still arises, with mortality rate between 18-40% and neurological sequel in developing countries reached between 30-50%. Cytology analysis of cerebrospinal fluid has difficulties in differentiating bacterial meningitis from viral meni...
The Role of Sheffield Score as a Predictor of Endoscopy Requirement in Children with Gastrointestinal Bleeding in Dr. Moewardi General Hospital
Dian Novita Sari1, Bambang Soebagyo1, Hari Wahyu Nugroho1
The Role of Sheffield Score as a Predictor of Endoscopy Requirement in Children with Gastrointestinal Bleeding in dr. Moewardi General Hospital Dian Novita Sari, Bambang Soebagyo, Hari Wahyu Nugroho Departement of Child Health, Medical Faculty of Sebelas Maret University Pediatric Gastroenterol...
Ten Years Data of Child Abuse and Neglect Cases Managed at the First Hospital Based Child Protection Unit in Pakistan
Naeem Zafar1, Mehek Naeem1, Andleeb Zehra2, Mahrukh Khalid1
Managing child abuse and neglect cases is extremely difficult in low-income countries, with daunting challenges in health, social welfare, education, and legal systems. PAHCHAAN initiated Child Protection Unit (CPU) at Children Hospital Lahore, Pakistan is the first hospital-based Child Protection U...
A RARE CASE OF RENAL GLYCOSURIA IN A 3 YEARS 2 MONTHS OLD CHILD.
Manoj1, Sreekanth1, Vivek Sharma1, Smriti Nath1
We present a 3 year & 2 months old male child otherwise healthy and developmentally normal incidentally found to have 3+ urine glucose on dipstick. His blood sugar & HbA1C was normal. There was no other evidence of any tubulopathy. Hence the possibility of Non-diabetic Renal Glycosuria was kept, whi...
A Rare Case of Infantile Systemic Hyalinosis with Mutation in ANTXR2
Sunil V. Kapur1, Jitendra S. Oswal1, Vijay Viswanathan1
Dear Editor, I am pleased to submit a case report article entitled “A Rare Case of Infantile Systemic Hyalinosis with Mutation in ANTXR2 “ for consideration for publication in Asia Pacific Journal of Pediatrics and Child Health. Infantile systemic hyalinosis is an autosomal recessive rar...
Association Between Nutritional Status and Mucosal Gut Immune System in Elementary School in Manado
Jeanette I. Ch. Manoppo, SpA(K)1, Beatrice Koesmarsono1
Nutritional imbalances can affect mucosal gut immunity. Fecal calprotectin (FC) is one of biomarker protein that works as an innate immune system in the mucosal gut. This study aimed to evaluate the association between nutritional status and mucosal gut immune system in elementary school using FC co...
Volume 2, Oct-Dec 2019
Through adolescents eyes: Looking at NCDs from an adolescent perspective in the South East Asia region
Amy Eussen1, Ghaisani Fadiana2,3, Aman Pulungan1,2,3
We were all once young and it is our childhood and our adolescence that largely shapes the life we live, our health, and the opportunities we have....
Building resilience and ameliorating risk in Pacific Island children and young people in South Western Sydney
Dr Priyaneela Kamalanathan1, Dr Shanti Raman2
Our project aimed to describe the health status of Pacific Islander children and young people (PI ChYP) in South Western Sydney (SWS) through the collection of the best quantitative data and to use qualitative data gathered from key community stakeholders to explore the risk and resilience factors i...
Management of Cystic Fibrosis – Challenges in Pakistan
Dr. Bushra Rafique1, Dr Ahad Korar1, Dr Summan Sohail1
The objectives of this study were to find out incidence of Cystic Fibrosis among children who presented with triad of diarrhea, pneumonia and failure to thrive, to find out appropriate investigations and availability of medicines and tools for physiotherapy....
THE ASSOCIATION OF ALLERGIC DISEASE WITH EPILEPSY
Gregory Joey1, Diana Takumansang-Sondakh1, Raynald O. Takumansang1
Small studies have shown an increased risk of allergic disease in children with epilepsy and many studies still showing a conflicting result. The mechanism of the relationship between allergic disease and seizures remain undetermined. Many hypotheses the release of inflammatory cytokines during the ...
Viral Load by RT-PCR as a Marker of Severity in Children with Hepatitis A
Dr Ayub Ansari1, Dr Shrish Bhatnagar1, Dr Tasleem Raza1
To study the association between severity and viral load in children suffering from acute Viral A Hepatitis . 50 patients of Acute Viral A Hepatitis were enrolled into the study. They were divided into acute hepatitis(Group I), severe acute hepatitis (Group II) and fulminant hepatitis (Group III),...
Achondroplasia and Down Syndrome In An Infant: A Rare Co-Occurrence
Gizem Ürel-Demir1, Pelin Ozlem Simsek-Kiper1, Rahsan Gocmen2, Gulen Eda Utine1, Koray Boduroglu1
Achondroplasia and Down’s syndrome are among the most common and most recognizable genetic disorders. However, the co-occurrence of these common conditions in the same patient is quite rare. Advanced paternal and maternal age is an established risk factor for achondroplasia and Down’s syndrome, ...
Hemoglobinuria in a child with Sickle β-Thalassemia trait
Srinivasan Thiagarajan1, Delhi kumar CG1, Ashritha Avalareddy1
A 7 year old male child who is a known case of sickle β-thalassemia presented with hemoglobinuria following packed red blood cell transfusion one week prior to the clinical presentation. He was diagnosed as a case of delayed haemolytic transfusion reaction (DHTR) which is extremely rare. The child ...
Diabetic Ketoacidosis with Extreme Hypernatremia in a 13-Year-Old Girl
Dr. Vandana Yadav1, Dr. Jaswir Singh1
Introduction: The most common sodium change observed in diabetic ketoacidosis (DKA) is hyponatremia with corrected sodium being in the eunatremic range. Although mild hypernatremia can be seen in 30% of patients presenting with DKA, extremely severe hypernatremia in the range of 190 mEq/L in DKA has...
Jacobsen Syndrome in a Filipino Child
Dr. Ebner Bon G. Maceda1,2, Dr. Leniza De Castro-Hamoy1,2
Background: Jacobsen syndrome (JS) is a chromosomal abnormality syndrome, which is caused by the partial deletion of the long arm of chromosome 11. This can be detected by standard karyotyping. Aims: This case aims to emphasize the value of a basic karyotype in establishing a cytogenetic diagnosis ...
Clinical Pediatrics in the Philippines: Parental Assent and Consent
Cyrus Cesar R. Tejam1
The involvement of children in the acceptance or refusal of any proposed plan of management in the Philippines is discussed. The practice of pediatrics includes patients who can already sign the informed consent form on their own and those patients that require a parent or legally authorized represe...
Volume 2, Jul-Sep 2019
Intermittent fasting and low-carbohydrate diet to improve cardiovascular risk factor in obese adolescent
Piprim Basarah Yanuarso1, Aryono Hendarto1, Aman Bhakti Pulungan1
Background: The prevalence of obesity in children and adolescent are increasing during recent years. Youth obesity is a risk for obesity in adulthood and associated to the development of cardiovascular risk factor. Increasing inflammation and oxidative stress in obesity have principal roles in patho...
A PILOT STUDY INVESTIGATING THE RELIABILITY AND FEASIBILITY OF MEASURING TIBIAL LENGTH AND RECUMBENT LENGTH IN CHILDREN AND YOUNG ADULTS WITH CEREBRAL PALSY
Dr Justine McCallum, Dr Phillipa Clark, Dr Rachael McLean, Catherine Wheeler, Dr Peter Reed.
Aim: To investigate the validity and feasibility of using tibial and recumbent length measurements in children with Cerebral Palsy (CP) in the outpatient clinic setting. Method: Participants with a primary diagnosis of Cerebral Palsy (CP) aged between 2-20 years of age (n=38) were recruited fro...
Karyotype, Phenotype Characteristics, and Quality of Life in Adolescents with Turner Syndrome; Are They Related?
Novina Novina1,Hartono Gunardi2,Aman B. Pulungan2
Background: Turner syndrome is characterized by the absence of part or the entire X chromosome in a woman and categorized as classical and mosaic based on karyotype. Comorbidities such as difficulty in learning and ear or cardiovascular abnormalities may affect the patient’s quality of life (QoL)....
Haemoglobin Level and Nutritional Status Changes Among Under-Five Children Treated with Antituberculosis Therapy in Cirebon
Arifah Nur Shadrina, Tuti Atikah
Children with TB are more susceptible to have anaemia that can lead to immunosuppression. However, the evolution of TB-associated anaemia with short-term combination antituberculosis therapy in children remains poorly quantified. This manuscript touches on an important topic related to tuberculosis ...
Management of Patients with Hemophilia in Oral Surgery
Melisa Ruth1, Prihartiningsih1, Elizabeth Riyati Titi Astuti1
Management of Patients with Hemophilia in Oral Surgery...
DE QUERVAIN’S THYROIDITIS – DON’T MISS IT IN CHILDREN
Dr Geetha M, Dr Kiran B, Dr Madhusmitha Jen
Unna Thost Syndrome is Palmo Plantar Keratoderma (PPK) of diffuse non epidermolytic type inherited in autosomal dominant fashion. We had a seven year old boy born to second degree consanguineous parents had palmoplantar keratoderma with hyperhidrosis with positive family history. He was promptly dia...
Caffey disease with acute sialadenitis: A diagnostic challenge!
Sunil V. Kapur1, Jitendra S. Oswal1,Dr Vibha Bafna 1
In this case report, we highlight that clinical awareness of the existence of this unique condition and its typical clinicoradiological profile avoids children being subjected to unnecessary invasive investigations. The aim of this case report is to alert paediatricians of the occurrence of acute si...
Volume 2, Apr - Jun 2019
Effect of Kangaroo Mother Care on neonatal health outcomes in rural Pakistan, A Randomized Controlled Trial
Muhammad Atif Habib1, 2, Kirsten I Black1, Shabina Ariff 2, Sajid Bashir Soofi2, Mushtaq Mirani2, Fariha Shaheen2, Amjad Hussain2, Zulfiqar A Bhutta2, Camille Raynes-Greenow3
Neonatal infections contribute significantly to neonatal mortality especially in developing countries. Delivering simple evidence based interventions has the potential to reduce the burden of neonatal infections and consecutively of neonatal mortality....
Assessment of Academic Performance of Licensed Athletes
Zehra Aycan1, Sinem Akgül2, Selçuk Gençay3, Nuray Kanbur4, Orhan Derman5
Physical activity and sports can be used to reduce stress and anxiety by increasing aerobic capacity and muscle endurance, gain positive behavioral changes and improve their self-discipline, use time well, adopt positive lifestyle such as regular eating and sleeping, which will result in an increase...
Height at three years of Highly active antiretroviral has a strong correlation with height at diagnosis in children with HIV infection
Ketut Dewi Kumara Wati1,2, Putu Diah Vedaswari2, Ida Bagus Ramajaya Sutawan2, I Wayan Eka Satriawibawa2, Meita Dhamayanti1,3, Budi Setiabudiawan1,3, Ida Parwati1,4
This study highlighted the persistence of growth faltering in children with HIV infection despite the commencement of highly active anti retro viral therapy. Over three years observation, we found that the height was remained in strong correlation with height at diagnosis where slow growth normally ...
Kartagener’s Syndrome – a triad or tetrad?
AKSHAY MEHTA1, LAKSHAY MEHTA1, JYOTI GUPTA2, BHAWNA MALIK3
Kartagener’s Syndrome – a triad or tetrad? Kartagener’s syndrome is an autosomal recessive disease characterized by triad of situs inversus, bronchiectasis and sinusitis. This anarchy affects the activity of ciliary cytoskeletal proteins important for the movement of cilia, thus causing mul...
Volume 2, Jan - Mar 2019
The effect of alternate-day corticosteroids on linear growth in childhood nephrotic syndrome
R.S. Thalgahagoda1, A.H.H.M. Jayaweera1, Y.A. Illangasekera2, A.S. Abeyagunawardena1
This study explains the negative effects of alternate-day corticosteroids on linear growth in a stable population of patients with steroid dependent nephrotic syndrome (SDNS) in Sri Lanka. The difference in median height velocities was pronounced between test and control groups, which was even evide...
APPA Program Focus: Answer to The Region’s Unique Challenges
Aman B Pulungan1
For the past 30 years, The Asia Pacific Pediatric Association (APPA) thrived to increase children’s health and welfare through regional collaboration. Health inequalities occur among and within regions of Asia Pacific; steps must be taken to minimize it by acknowledging the social determinants of ...
The Role of Pediatricians in Achieving Global Goals for Children
Errol Alden1
Children are the future, but pediatricians, who have devoted their lives to helping children survive and thrive, cannot alone guarantee children’s futures. The purpose of this paper is to inform all pediatricians of the current global efforts to improving the lives of children. It is our respon...
Achieving Best Medical Practice in ASEAN Economic Community Era
Aryono Hendarto1
The ASEAN Economic Community (AEC) Era is set to be legally formed in 2020 to prepare the ASEAN region in the era of economic and trade globalizations. The ASEAN Mutual Recognition Arrangements (MRAs) expanded into the medical field, allowing healthcare workers to practice in foreign countries....
Clinical Profile and IV Bisphosphonate Therapy in Children with Osteogenesis Imperfecta in Cipto Mangunkusumo Hospital
Aman B Pulungan1, Jose RL Batubara1, Bambang Tridjaja1, Frida Soesanti1, Ghaisani Fadiana1, Sirma I Mada2, Diadra Annisa2
Introduction: Osteogenesis imperfecta (OI) is a rare genetic disease affecting type I collagen in bone and skin. There is currently no cure for OI; however, studies showed that bisphosphonate administration confers some benefits. We aimed to know the characteristics of OI patients and the correlatio...
Volume 1, Oct-Dec 2018
Journey from Cell count to Metabolomics in the diagnosis of Neonatal Sepsis
Khalid N Haque
Neonatal sepsis remains a global challenge due to its high mortality and morbidity. One of the reasons for the high loss of neonatal life is the lack of early objective diagnostic biomarkers. The commonly routine tests used currently lack diagnostic certainty. However, emerging technologies like pro...
The effect of leuprolide acetate treatment on luteinizing hormone suppression in children with central precocious puberty: A systematic review and meta-analysis
Aman B Pulungan1, Ratna Dewi Artati2, Kuntjoro Harimurti3
Central precocious puberty (CPP) is a characteristic development of sexual puberty as a consequence of premature activity of hypothalamic-pituitary-gonadal axis (HPG axis) before eight years old for girls or nine years old for boys. Several studies have showed different results in Leuprolide Acetate...
Comparison of Dietary Sources of Iron, Nutritional Status and Family Factors Between Anemic and Non-anemic Children in Sorong, West Papua Province, Indonesia
Bagus W. Arundito1, Agus Senolinggi1, Endy P. Prawirohartono2,
Prevalence of anemia among 6-59 month of age children was 65%. Non anemic children consumed more liver, egg and tempeh. Related socioeconomic factors were antenatal care, iron supplementation of mother during pregnancy, family income, and stunting....
A Novel Three Way Translocation in a Child with t(8:21) Acute Myeloid Leukemia (AML-M2) Involving 6q27 with Loss of Y chromosome
Mohammed Ramzan1, Mohammed Lukman3, Monica Singh3, Satyendra Katewa1
The typical t(8;21) (q22;q22) abnormality is associated with acute myeloid leukemia with maturation (AML-M2 based on the French-American-British classification). This protein regulates proliferation, the differentiation, and the viability of leukemic cells. Method: We report a case of 9-year-old boy...
Volume 1, July-Sept 2018
What can Pediatricians do to address child health in South and Southeast Asia?
Zulfiqar A Bhutta
Despite the remarkable reduction in under 5 child mortality globally in the wake of the Millennium Development Goals (MDGs), a little under 6 million children still perish every year before reaching their fifth birthday. A large proportion, almost 46% die within the neonatal period (the first 28 day...
Awareness about Sickle Cell Anaemia in young adults in Amravati
Naresh B. Tayade1, Manjusha N. Tayade2
Sickle cell disease continues to be a global health problem that presents major challenges to our health care systems. The reviewed Sickle Cell Disease(SCD) literature expresses a dire need for more public education and awareness on SCD Misconceptions of sickle cell disease have significantly contri...
Fluid Management in Patients with Dengue Hemorrhagic Fever
H.M.T.W.Seneviratne1, G.D.I.Kumara2, K.Ravirajah3, K.M.K.Somaratne4, D. Mendis3
Iatrogenic fluid overload in Dengue Haemorrhagic Fever (DHF) is well recognized. To address this, restriction of total fluid volume in the critical phase (TFV) to maintenance plus 5% of the body weight (M+5%) was adopted in Sri Lanka in 2010. The purpose of this study was to assess the TFV and how ...
Antibiotic Prescribing Practice for Paediatric Outpatients across Non-specialised Regional Hospitals in Kedah State, Malaysia.
Guo Hong Tan1, Huan Keat Chan2, Linda Mohd Jamal3, Muhammad Hazwan Hamidon3, Aun Chyi Oi4, Yae Tyug Yap4, Yu Hsuan Khoo5
Background The Malaysia National Antibiotic Guidelines (NAG) is used to guide antibiotic prescribing, especially among public healthcare facilities without an in-house infectious disease specialist, setting-based antibiotic guidelines and clinical microbiology services. Aims To explore the patte...
Late onset anti- N-methyl-D-aspartate receptor encephalitis following Japanese encephalitis
Hnin Wint Wint Aung1, Kyaw Linn1, Aye Mya Min Aye1, Chaw Su Hlaing1, Aye Mu Saan1, Khine Mi Mi Ko1, Myo Thiri Swe1, Cho Thair1, Yi Yi Mar1, Nway Nway1, Phyu Phyu Myint1, Ei Hnin Kyu1, Haymar Han1
Japanese encephalitis (JE) is one of the leading causes of viral encephalitis worldwide and affects mostly children. The patients with JE often have uniphasic illness with acute onset; however, some patients may have an early relapse after relatively partial recovery. Recent studies have also shown ...
Hand Foot Mouth Disease – Experience of epidemic in children in Lahore, Punjab, Pakistan
Muhammad Ashraf Sultan1, Muhammad Faheem Afzal2
Hand Foot Mouth Disease (HFMD) is a viral infection first described by Robinson et al in 1957 as an outbreak in Toronto. The infectious disease was characterized by vesicles inside the mouth and on the hands and feet and was found to have been caused by Coxsackievirus (CVA) ...
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