www.apjph.comwww.apjph.com
Abstract Ref Number = APCP1086
Poster Presentation
NEPHROTIC SYNDROME WITH FOCAL SEGMENTAL GLOMERULOSCLEROSIS
Nur Liya Abd Kadir,Syarifuddin Rauf
Departement of Child Health Faculty of Medicine Hasanuddin University Dr Wahidin Sudirohusodo Hospital Makassar Indonesia Departement of child Health Faculty of Medicine Hasanuddin University Dr Wahidin Sudirohusodo Hospital Makassar Indonesia
Background : Nephrotic syndrome (NS) is characterized by proteinuria (>50 mg/kg/24 hr), edema, hypoalbuminemia (<2.5 g/dl), and hypercholesterolemia. In hystopatology pattern of Nephrotic syndrome idhiopatic, about 20% are Focal Segmental Glomerulosclerosis (FSGS) in pediatric nephrotic syndrome. Approximately 80% of nephrotic syndrome with FSGS is steroid resistant.
Case Presentation Summary : A 13 years and 1 month old girls admitted to the hospital due to swelling on the eyelid since 3 months before. She was given prednisone for 5 weeks before admitted. Physical examination revealed edema on the face. Laboratory data revealed serum albumin 3.2 g/dl, serum cholesterol 300 mg/dl, and urinary albumin 3+, Esbach’s test 0.5 g/24 hr, kidney biopsy result is Nephrotic syndrome with focal segmental sclerosis appearance. The patient was treated with methylprednisolone, low protein diet 1.5-2 g/kg/day, and reduction of salt intake (1-2 g/day).
Learning Points/Discussion : • FSGS is the second most common histopathologic lesion of nephrotic syndrome idiophatic after minimal change. • Clinical manifestations of FSGS in this patient are eyelid edema and face, hypoalbuminemia, hypercholesterolemia, proteinuria, and kidney biopsy result was nephrotic syndrome with focal segmental sclerosis appearance. • Prognosis is dubia if there is no remission in the treatment period.
Keywords: Nephrotic syndrome Focal Segmental Glomerulosclerosis Kidney biopsy
Disclaimer: The Views and opinions expressed in the articles are of the authors and not of the journal.
Editor-In-Chief
Journal Office
Mid City Hospital, 3-A Shadman II
Jail Road, Lahore ,Pakistan
Mid City Hospital, 3-A Shadman II
Jail Road, Lahore ,Pakistan
Managing Editor
Dr. Intan Juliana Abd Hamid
Support & Help
Support & Help
Assistant Editor
Dr. Sadia Shabbir Hussain
Support & Help
Support & Help
Digital Content Editor
Dr. Khalid Masud
Administrator
Administrator